Media
A hand-picked listening and viewing path through the longevity field — from foundational shows you can subscribe to, to specific episodes that pair well with course modules. Mix of the optimistic (Sinclair, de Grey) and the skeptical (Attia, Kaeberlein, Brenner).
Shows worth subscribing to
Ongoing series with consistent signal-to-noise.
Lifespan with David Sinclair
Sinclair's own 8-episode primer on the information theory of aging, NAD+, sirtuins, sensors of aging, and what he personally does. Best single starting point for his framework.
The Drive
Deep, technical interviews on healthspan, metabolism, exercise, lipidology, dementia prevention, and clinical interpretation of biomarkers. Sets the bar for evidence-graded discussion.
FoundMyFitness
Mechanistic deep dives on micronutrients, sauna, omega-3, exercise, fasting, and hallmarks of aging. Strong literature curation and member Q&As.
Optispan with Matt Kaeberlein
Geroscience from the Dog Aging Project PI. Pragmatic takes on rapamycin, supplements, hype vs. evidence, and the politics of longevity research.
Live Long and Master Aging (LLAMA)
Long-running interview podcast with longevity scientists, clinicians, and biotech founders — wide coverage including Aubrey de Grey, Nir Barzilai, Brian Kennedy, Andrea Maier.
Foresight Longevity Channel
Long-form talks and panels with researchers across rejuvenation biotech — including Aubrey de Grey, partial reprogramming groups, and damage-repair labs.
Huberman Lab
Neuroscience-flavored health podcast. Best episodes for this course are the Sinclair, Attia, Patrick, and Galpin interviews on aging, exercise, and recovery.
Lifespan News (LEAF)
Short weekly news roundups on rejuvenation science, biotech funding, and clinical-trial updates from the Life Extension Advocacy Foundation.
Single episodes worth your time
Standalone episodes that map onto course themes — sequenced to span Sinclair, de Grey, and the skeptics.
Why We Age — and Why We Don't Have To
Sinclair's clearest single-episode statement of the loss-of-information hypothesis, sirtuins, and the case for reprogramming.
David Sinclair: The Biology of Slowing & Reversing Aging
Long-form, well-structured tour of Sinclair's lab work and personal protocol — good audio companion to Module 09.
Aubrey de Grey: Rejuvenation Biotechnology and the SENS Approach
Concise primer on the seven categories of aging damage and the Robust Mouse Rejuvenation combination trial.
Aubrey de Grey on Longevity Escape Velocity
de Grey explains why combinatorial damage-repair (not single drugs) is the credible path to large healthspan gains.
Peter Attia × David Sinclair — NAD, Sirtuins, Reprogramming
Attia presses Sinclair on evidence quality — the best single episode for hearing both sides of the resveratrol/NMN debate.
Matt Kaeberlein on Rapamycin and the Dog Aging Project
The reference take on what rapamycin does and doesn't do, from the field's most outspoken methodologist.
Nir Barzilai — Metformin, Centenarians, and the TAME Trial
Why the TAME trial matters even if metformin's effect is modest — and what 'aging as an indication' would unlock.
Steve Horvath — Epigenetic Clocks and Biological Age
Foundational episode for understanding what biological-age tests actually measure, and how to interpret them.
Valter Longo — Fasting-Mimicking Diet and Longevity
Mechanism + clinical-trial evidence for the 5-day fasting-mimicking diet, with Attia's skeptical pressure-testing.
Morgan Levine — Phenotypic Age and DunedinPACE
Practical guide to which biological-age clock to use, how to interpret, and the limits of current commercial tests.
Charles Brenner vs. NAD Hype
Counterweight to the Sinclair narrative — Brenner discovered NR and is sharply critical of NMN marketing claims.
Andrea Maier — Translating Geroscience into the Clinic
What a real geroscience clinic looks like — combination interventions, biomarkers, and patient selection.
Suggested listening order
- Sinclair on Lifespan ep. 1 — get the information-theory framing.
- Sinclair × Huberman — fill in protocol and lab detail.
- Attia × Sinclair (The Drive #70) — hear the rigorous pushback.
- de Grey on LLAMA + Foresight — switch frameworks to damage repair and LEV.
- Kaeberlein + Brenner — calibrate enthusiasm with the field's leading skeptics.
- Horvath + Levine — ground everything in measurable biological-age endpoints.